
Dr Shivan Sivakumar
Consultant Medical Oncologist · Associate Professor in Oncology
University of Birmingham · University Hospitals Birmingham
MBBS, BMedSci, PhD, FRCP
A personalised second opinion service
More than 80% of patients make changes to their treatment plan based on our reports. — Astron patient data, 2024–26
We look at what's driving your cancer at the molecular level, have a panel of world-leading oncologists and researchers review your case, and turn it into a clear, evidence-ranked second opinion you can take to your own doctor.
We study your cancer at the molecular level to find the specific things driving it.
A panel of world-leading oncologists and researchers reviews your test results and writes a second opinion based on your results.
A clear report you can take to your own doctor, and we'll talk it through with them, showing the treatments and trials worth considering for you.
Our clinicians & researchers have worked, studied & published at
We analyse your unique molecular data, have a panel of world-leading oncologists and researchers review it, then give you a clear report to act on with your existing care team, who we can speak to directly.
Sign up online and tell us about your diagnosis. Upload any records and test results you already have.
Week 1We review your case and use any molecular testing you've already had. If you need more, we arrange it.
Weeks 1–3Our engine analyses your results. Then a panel of world-leading oncologists and researchers reviews the findings and signs off on your written second opinion.
Week 3You get a clear, prioritised report covering the treatments and trials that could apply to you, ready to take to your own doctor. We can also speak to your care team directly to help put it into action.
Week 4More than a standard report. We analyse your molecular data, have a panel of world-leading oncologists and researchers review and sign it off, and give you a report you can take straight to your own doctor.
First we check whether you need new testing. If you've already had molecular testing, we use it. If not, we arrange a full, exhaustive molecular test to analyse the unique combination of drivers of your cancer.
Our engine turns your molecular data into a ranked, evidence-graded shortlist: any targeted therapies and clinical trials worth considering for you, all explained in plain, clinician-readable terms.
A panel of world-leading oncologists and researchers reviews the analysis and signs it off, so your second opinion carries real clinical weight. You get a well-evidenced, personalised second opinion and, with your consent, we speak to your own doctor directly. They stay the one who prescribes or enrols you in a trial.
Every Astron second opinion is reviewed and signed off by a molecular tumour board of world-leading oncologists and researchers. These are some of the specialists who would work on your case.

Consultant Medical Oncologist · Associate Professor in Oncology
University of Birmingham · University Hospitals Birmingham
MBBS, BMedSci, PhD, FRCP
Consultant Clinical Oncologist
The London Clinic · Cromwell Hospital, London
MBBS, MD, MRCP, FRCR

Consultant Medical Oncologist
The London Clinic · Cromwell Hospital, London
MBBS, PhD, FRCP
Consultant Haemato-Oncologist · Senior Lecturer in Haemato-oncology
St Bartholomew's Hospital, Barts Health NHS Trust · Queen Mary University of London
MB ChB, FRCP, FRCPath, PhD
A free guide to the questions worth asking at your next appointment — so you understand your options and stay in control of the decisions ahead.
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If you are deciding whether this is right for you, book a free 20-minute call with our care lead. Otherwise, start your package and we will be in touch within one working day.